STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menG/ubiEMenaquinone/ubiquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (243 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.915
ggcX
Vitamin K-dependent gamma-glutamyl carboxylase is involved in the Vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues in various proteins. It converts glutamate residues to gamma-carboxyglutamate; Contains six transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
     
 0.901
ytfG
YtfG belongs to the NmrA-type oxidoreductase family, but its exact function is unknown; Localized in the cytoplasm; Family membership.
    
  0.901
CAZ98775.1
NmrA family oxidoreductase; Conserved protein belonging to the NmrA-type oxidoreductase family, but its exact function is unknown. NmrA is a negative transcriptional regulator involved in the control of nitrogen metabolite repression in various fungi. Its crystal structure has revealed an unexpected similarity to the short-chain dehydrogenase/reductase (SDR) family. NAD binds to NmrA in vitro. Localized in the cytoplasm; Family membership.
    
  0.901
wrbA
NAD(P)H dehydrogenase [quinone]; The enzyme catalyse the NAD(P)H-dependent two-electron reductions of quinones; It apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons to protect cells against damage by free radicals and reactive oxygen species; It has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone; Uses a FAD cofactor; Localized in the cytoplasm; High confidence in function and specificity.
     
 0.900
kdsD
Arabinose 5-phosphate isomerase or Phosphoarabinoisomerase is involved in the lipopolysaccharide (LPS) biosynthesis; It catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate; Contains a N-terminal SIS (Sugar ISomerase) domain that is a phosphosugar-binding domain and a C-terminal CBS (cystathionine-beta-synthase) domans; Belongs to the SIS family; Localized in the cytoplasm; High confidence in function and specificity.
 
   0.665
porT
PorT is essential for the transport of some proteins across the outer membrane from the periplasm to the cell surface; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity.
       0.658
trkA
TrkA is part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH. Localized in the cytoplasm; High confidence in function and specificity.
       0.536
trkH
TrkH is a low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity. Features ten transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.485
ispB
Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity.
 
  
 0.483
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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