STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpeARibulose-phosphate 3-epimerase converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Pentose phosphate pathway; Adopts a a TIM barrel fold; Localized in the cytoplasm; High confidence in function and specificity. (226 aa)    
Predicted Functional Partners:
tktA
Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity.
 
 0.996
rpiB
Ribose 5-phosphate isomerase B catalyses the conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Forms a homodimer; Localized in the cytoplasm; High confidence in function and specificity.
 
 0.985
tktB
Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.955
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 0.952
araB
Ribulokinase catalyzes the phosphorylation of ribulose. This is the second step of the arabinose catabolism. AraB belongs to the FGGY family of the carbohydrate kinases; High confidence in function and specificity.
   
 0.951
gndA
6-Phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.947
xylB-2
Xylulose kinase is involved in xylose catabolism. It catalyzes the reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate. Localized in the cytoplasm; High confidence in function and specificity.
 
 
 0.935
araD
L-ribulose-5-phosphate 4-epimerase catalyzes the conversion of L-ribulose 5-phosphate into D-xylulose 5-phosphate. This is the third step of the L-arabinose catabolism. AraD belongs to the class II aldolase family. Binds one zinc ion by subunit. Localized in the cytoplasm; High confidence in function and specificity.
    
 0.925
hxlA
3-Hexulose-6-phosphate synthase catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with HxlB, may act as a formaldehyde detoxification system. Localized in the cytoplasm; High confidence in function and specificity.
    
 0.904
engC
GTPase engC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
 
    0.871
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.