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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94845.1TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (29-114) and the Plug module (130-226) acting as a channel gate; The signal peptide is cleaved between the residues 24 and 25; Family membership. (793 aa)    
Predicted Functional Partners:
CAZ94844.1
Conserved hypothetical membrane protein; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.714
tonB1
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.507
ziaA
ZiaA is a P-type ATPase responsible for zinc efflux using ATP hydrolysis for energy. ZiaA controls zinc homeostasis. Belongs to the cation transport P-type ATPase family. Features six transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.490
CAZ97186.1
Large conserved protein that Seems to contain an N-terminal transmembrane segment and a C-terminal Blue (type 1) copper domain from the plastocyanin/azurin family; Putatively localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.473
CAZ96800.1
TonB-like protein; TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Energy flows from the cytoplasmic membrane into the outer membrane via a complex consisting of TonB, ExbB and ExbD proteins which are anchored in the cytoplasmic membrane. TonB interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates; Although belonging to the TonB family, this protein seems to contain a signal peptide cleaved between the residues 17 and 18, which is unsual for c [...]
 
 
 0.464
tonB2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.454
CAZ94986.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership.
  
 
   0.401
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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