STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dusAtRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (320 aa)    
Predicted Functional Partners:
CAZ98419.1
Hypothetical Co-chaperone that could be part of a chaperone (protein folding) system; Contains a N-terminal 'J' domain; Belongs to the J-protein family, type 3 subgroup; Localized in the cytoplasm; Function unclear.
 
   
 0.601
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 
 0.555
panC
Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
    0.539
CAZ98434.1
DUF6 family protein; Conserved membrane protein containing two DUF family domains. Features ten transmembrane helices. Localized in the cytoplasmic membrane; Family membership.
 
    0.524
CAZ94851.1
Protein containing three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein.
       0.462
panE
2-Dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.459
CAZ96701.1
Protein that contains five repeats of twenty aminoacids The MORN (membrane occupation and recognition nexus) repeats would contribute to the cytoplasmic membrane binding, possibly by interacting with phospholipids; Putative lipoprotein signal peptide cleaved between the residues 18 and 19; possibly localized in the outer membrane; Conserved hypothetical protein.
 
     0.429
CAZ94844.1
Conserved hypothetical membrane protein; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
     0.417
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.402
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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