| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAZ94152.1 | CAZ94153.1 | ZOBELLIA_79 | ZOBELLIA_80 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Conserved hypothetical protein. Localized in the cytoplasm. | 0.553 |
| CAZ94152.1 | CAZ98888.1 | ZOBELLIA_79 | ZOBELLIA_4753 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.406 |
| CAZ94152.1 | hemN-2 | ZOBELLIA_79 | ZOBELLIA_2274 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.508 |
| CAZ94152.1 | mrpA | ZOBELLIA_79 | ZOBELLIA_1290 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Protein mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | 0.543 |
| CAZ94152.1 | pnpA | ZOBELLIA_79 | ZOBELLIA_768 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.418 |
| CAZ94152.1 | rlmN | ZOBELLIA_79 | ZOBELLIA_817 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Radical SAM family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.599 |
| CAZ94152.1 | rpmE | ZOBELLIA_79 | ZOBELLIA_81 | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | Protein L31 is a part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L31p family, type B subfamily; Localized in the cytoplasm; High confidence in function and specificity. | 0.405 |
| CAZ94153.1 | CAZ94152.1 | ZOBELLIA_80 | ZOBELLIA_79 | Conserved hypothetical protein. Localized in the cytoplasm. | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | 0.553 |
| CAZ94153.1 | rpmE | ZOBELLIA_80 | ZOBELLIA_81 | Conserved hypothetical protein. Localized in the cytoplasm. | Protein L31 is a part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L31p family, type B subfamily; Localized in the cytoplasm; High confidence in function and specificity. | 0.547 |
| CAZ98888.1 | CAZ94152.1 | ZOBELLIA_4753 | ZOBELLIA_79 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | 0.406 |
| CAZ98888.1 | hemN-2 | ZOBELLIA_4753 | ZOBELLIA_2274 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.596 |
| CAZ98888.1 | pnpA | ZOBELLIA_4753 | ZOBELLIA_768 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.543 |
| CAZ98888.1 | rlmN | ZOBELLIA_4753 | ZOBELLIA_817 | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Radical SAM family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.662 |
| hemN-2 | CAZ94152.1 | ZOBELLIA_2274 | ZOBELLIA_79 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | 0.508 |
| hemN-2 | CAZ98888.1 | ZOBELLIA_2274 | ZOBELLIA_4753 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.596 |
| hemN-2 | pnpA | ZOBELLIA_2274 | ZOBELLIA_768 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.632 |
| hemN-2 | rlmN | ZOBELLIA_2274 | ZOBELLIA_817 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Radical SAM family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.761 |
| mrpA | CAZ94152.1 | ZOBELLIA_1290 | ZOBELLIA_79 | Protein mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | 0.543 |
| pnpA | CAZ94152.1 | ZOBELLIA_768 | ZOBELLIA_79 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership. | 0.418 |
| pnpA | CAZ98888.1 | ZOBELLIA_768 | ZOBELLIA_4753 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Alpha/beta barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.543 |
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