Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.

Peptidoglycan synthetase, family GT51; Enzyme essential for the formation of a septum of the murein sacculus. Synthetizes the cross-linked peptidoglycan from the lipid intermediates; Contains in its N-terminal half part a transmembrane segment and an penicillin insensitive transglycosylase domain (formation of linear glycan strands). In its C-terminal half part, a penicillin- sensitive transpeptidase domain (cross-linking of the peptide subunits) and a PASTA domain that binds the beta-lactam stem are present; Belongs to the family 51 of glycosyl transferases (GT51); Except for the cyto [...]

Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.

UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.

FtsW is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division; Contains ten transmembrane segments; Belongs to the ftsW/rodA/spoVE family; Localized in the cytoplasmic membrane; High confidence in function and specificity.

Cell division protein DivIC; DivIC is required for septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. Localized in the cytoplasm; High confidence in function and specificity.

Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

Phospho-N-acetylmuramoyl-pentapeptide- transferase, family GT4; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.

Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.