STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94153.1Conserved hypothetical protein. Localized in the cytoplasm. (391 aa)    
Predicted Functional Partners:
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
  
 0.788
prsA
Ribose-phosphate pyrophosphokinase converts the D-ribose 5-phosphate to 5-phospho-alpha-D-ribose 1-diphosphate in the Pentose phosphate pathway. Utilized by both the de novo and the salvage pathways by which endogenously formed or exogenously added pyrimidine, purine, or pyridine bases are converted to the corresponding ribonucleoside monophosphates; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.786
rmlB
dTDP-glucose 4,6-dehydratase converts the dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose. This enzyme is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the NAD dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasm; High confidence in function and specificity.
    
 0.613
maeB
Bifunctional protein: Malic enzyme (N-terminal domain, 1 to 550) and Phosphate acetyl/butaryl transferase (C-terminal domain, 550 to 765); High confidence in function and specificity.
  
 
 0.594
CAZ97869.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.590
CAZ94152.1
MiaB-like tRNA modifying protein; Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership.
  
    0.553
rpmE
Protein L31 is a part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L31p family, type B subfamily; Localized in the cytoplasm; High confidence in function and specificity.
       0.547
atpE1
ATP synthase, F0 sector C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
 
   
 0.537
lpxC/fabZ4
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily.
 
   
 0.524
CAZ97169.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.517
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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