STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsLHypothetical protein that could be FtsL involved in coupling of cell division and peptidoglycan physiology; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein. (109 aa)    
Predicted Functional Partners:
ftsI
Peptidoglycan synthetase, family GT51; Enzyme essential for the formation of a septum of the murein sacculus. Synthetizes the cross-linked peptidoglycan from the lipid intermediates; Contains in its N-terminal half part a transmembrane segment and an penicillin insensitive transglycosylase domain (formation of linear glycan strands). In its C-terminal half part, a penicillin- sensitive transpeptidase domain (cross-linking of the peptide subunits) and a PASTA domain that binds the beta-lactam stem are present; Belongs to the family 51 of glycosyl transferases (GT51); Except for the cyto [...]
 
     0.864
ftsW
FtsW is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division; Contains ten transmembrane segments; Belongs to the ftsW/rodA/spoVE family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
     0.833
murE
UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
    0.824
ftsQ
Possible cell division protein ftsQ; This hypothetical protein could be the FtsQ protein involved in septum formation. Could interact with ftsZ, ftsA, and penicillin binding protein 3. The function of FtsQ is unknown; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
     0.823
gldI
GldI, lipoprotein required for gliding motility, contains a Peptidyl-prolyl cis-trans isomerase (PPIase) domain; PPIases catalyze the peptidyl-prolyl isomerisation of the peptide bond preceding proline that is stabilised in the cis conformation in oligopeptides; GldI may be involved in folding cell envelope protein components of the motility machinery; Signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane or/and cytoplasmic membrane; High confidence in function and specificity.
  
     0.765
mraW
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
       0.753
mraZ
Protein that could play a role in cell-wall biosynthesis and/or cell division. However, to date, there has been no clear functional assignment provided for MraZ protein. MraZ is a homooctamer or homododecamer to forms a ring; Localized in the cytoplasm; Function unclear.
       0.753
CAZ94114.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein.
 
     0.732
CAZ95844.1
Conserved hypothetical protein; Localized in the cytoplasm.
  
     0.731
murD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
       0.725
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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