node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAZ95297.1 | idsA | ZOBELLIA_1241 | ZOBELLIA_1951 | Prenyltransferase family protein; Multi-pass membrane protein that contains eight transmembrane segments; Localized in the cytoplasmic membrane; Family membership. | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | 0.432 |
CAZ95297.1 | ispB | ZOBELLIA_1241 | ZOBELLIA_816 | Prenyltransferase family protein; Multi-pass membrane protein that contains eight transmembrane segments; Localized in the cytoplasmic membrane; Family membership. | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | 0.858 |
crtB | idsA | ZOBELLIA_2973 | ZOBELLIA_1951 | The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity. | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | 0.915 |
crtB | ispB | ZOBELLIA_2973 | ZOBELLIA_816 | The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity. | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | 0.915 |
crtB | uppS | ZOBELLIA_2973 | ZOBELLIA_2457 | The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity. | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.833 |
hemCD | idsA | ZOBELLIA_1862 | ZOBELLIA_1951 | Porphobilinogen deaminase / Uroporphyrinogen-III synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | 0.508 |
hemCD | ispB | ZOBELLIA_1862 | ZOBELLIA_816 | Porphobilinogen deaminase / Uroporphyrinogen-III synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | 0.577 |
idsA | CAZ95297.1 | ZOBELLIA_1951 | ZOBELLIA_1241 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | Prenyltransferase family protein; Multi-pass membrane protein that contains eight transmembrane segments; Localized in the cytoplasmic membrane; Family membership. | 0.432 |
idsA | crtB | ZOBELLIA_1951 | ZOBELLIA_2973 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity. | 0.915 |
idsA | hemCD | ZOBELLIA_1951 | ZOBELLIA_1862 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | Porphobilinogen deaminase / Uroporphyrinogen-III synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.508 |
idsA | ispB | ZOBELLIA_1951 | ZOBELLIA_816 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | 0.925 |
idsA | ndkA | ZOBELLIA_1951 | ZOBELLIA_3698 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.560 |
idsA | rpsE | ZOBELLIA_1951 | ZOBELLIA_2527 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. | 0.516 |
idsA | uppS | ZOBELLIA_1951 | ZOBELLIA_2457 | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.977 |
ispB | CAZ95297.1 | ZOBELLIA_816 | ZOBELLIA_1241 | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | Prenyltransferase family protein; Multi-pass membrane protein that contains eight transmembrane segments; Localized in the cytoplasmic membrane; Family membership. | 0.858 |
ispB | crtB | ZOBELLIA_816 | ZOBELLIA_2973 | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity. | 0.915 |
ispB | hemCD | ZOBELLIA_816 | ZOBELLIA_1862 | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | Porphobilinogen deaminase / Uroporphyrinogen-III synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.577 |
ispB | idsA | ZOBELLIA_816 | ZOBELLIA_1951 | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | Bifunctional short chain isoprenyl diphosphate synthase; IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopenteny [...] | 0.925 |
ispB | menA | ZOBELLIA_816 | ZOBELLIA_4025 | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.835 |
ispB | ndkA | ZOBELLIA_816 | ZOBELLIA_3698 | Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.650 |