STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ94916.1Polysaccharide lyase, family PL9; This protein is modular with a N-terminal domain belonging to the family 9 of the polysaccharide lyases (23-622) and a C-terminal conserved domain of unknown function (661-915). The PL9 domain adopts a right handed parallel beta-helix fold. In contrast to other proteins from the PL9 family, a conserved domain of unknown function is inserted within loops of the beta-helix core (97-271). Such domain insertion in a beta-helix has been observed in the family GH82. Features a signal peptide cleaved between residues 23 and 24. Localized in the periplasm; Spe [...] (915 aa)    
Predicted Functional Partners:
CAZ94917.1
This conserved protein contains a C-terminal type-III fibronectin (FN3) domain. Structures of individual FN3 domains have revealed a conserved beta sandwich fold also found in bacterial glycosyde hydrolases and other proteins; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear.
 
     0.882
CAZ94992.1
Serine peptidase, family S8; Serine peptidase contains a catalytic triad in the order Asp, His and Ser in the sequence. Its structure consists of three layers with a seven-stranded beta sheet sandwiched between two layers of helices; Belongs to the family S8 of peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic membrane; Specificity unclear.
 
   0.794
porD
Beta-porphyranase D, family GH16; Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6- sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6- sulfate-(1->3)-beta-D-galactose.
  
     0.760
agaA
Beta-agarase A, family GH16; Cleaves the beta-1,4-linkages between beta-D-galactose and alpha-L-3,6-anhydro-galactose residues in agarose. Cleaves agarose in a random manner with retention of the anomeric-bond configuration, producing beta-anomers that give rise progressively to alpha-anomers when mutarotation takes place.
  
     0.728
porE
Beta-porphyranase E, family GH16; Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6- sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6- sulfate-(1->3)-beta-D-galactose.
  
     0.714
cgkA
Kappa-carrageenase, family GH16; Kappa-carrageenase Hydrolyses the 1,4-beta-D-galactosidic linkages in kappa-carrageenan giving the tetramer as the predominant product; Modular enzyme containing a N-terminal catalytic domain belonging to the family 16 of the glycoside hydrolases, a central Carbohydrate Binding Module of the family CBM16 and a C-terminal domain of unknown function; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space and possibly secreted in the outside medium; High confidence in function and specificity.
  
     0.710
CAZ94278.1
Conserved hypothetical protein; Contains a C-terminal domain of unknown function (100 aa) and a lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Belongs to the glycosyl hydrolase 43 family.
  
     0.702
CAZ95962.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.699
CAZ97735.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Conserved hypothetical protein.
  
     0.696
porA
Beta-porphyranase A, family GH16; Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6- sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6- sulfate-(1->3)-beta-D-galactose. Some longer oligosaccharides of even number of residues are also observed. Inactive on the non-sulfated agarose portion of the porphyran backbone. Displays a strict requirement for C6-sulfate in the -2 and +1-binding subsites.
  
     0.665
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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