STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msbAInvolved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane; Contains six N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA subfamily); High confidence in function and specificity. (607 aa)    
Predicted Functional Partners:
CAZ98414.1
The ABC-1 type transporters have their ABC membrane domain and their ABC ATPase domain fused in the same protein. They are involved in the efflux of compounds across the biological membranes or in targeting of membrane components; Contains five N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA); Family membership.
  
  
 
0.919
CAZ95817.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes of the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership.
 
  
0.830
pgcA
Phosphoglucomutase catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. It participates in both the breakdown and synthesis of glucose. Binds one magnesium as cofactor. Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.808
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.799
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
  
 0.715
arnC1
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase, family GT2; ArnC catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the family 2 of the glycosyltransferase (GT2); Contains three C-terminal transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
  
 0.663
CAZ94160.1
RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership.
       0.616
CAZ94162.1
Conserved hypothetical protein; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space.
       0.595
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
 
 0.581
CAZ94161.1
Conserved hypothetical membrane protein; Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.580
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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