STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ94945.1ABC transporter, permease component; ABC (ATP-binding cassette) transporters are responsible for translocation of a variety of compounds across biological membranes; Probably, this protein is the membrane component of an ABC importer; Contains a DUF140 domain and five transmembrane segments; Localized in the cytoplasmic membrane; Family membership. (233 aa)    
Predicted Functional Partners:
CAZ94946.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership.
 
 0.998
CAZ97879.1
Protein of unknown function that could be the periplasmic component of a ABC transporter (importer); Contains a Mce (mammalian cell entry) domain and one N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
 0.991
CAZ98020.1
ABC importer, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership.
 
 0.988
CAZ98019.1
ABC importer, periplasmic component; Periplasmic protein of unknown function anchored in the cytoplasmic membrane by a N-terminal transmembrane segment; could be involved in the uptake of organic solvents; Contains a Mce (mammalian cell entry) domain; Belongs to the periplasmic substrate-binding ABC transporter superfamily; Specificity unclear.
 
 0.973
CAZ98021.1
ABC importer, permease component; ABC (ATP-binding cassette) membrane protein responsible for translocation of a variety of compounds across biological membranes. Possibly involved in uptake of organic solvents such as gamma-Hexachlorocyclohexane or toluene for their utilization as source of carbon; Contains five transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; Belongs to the MlaE permease family.
  
  
 
0.924
CAZ97098.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership.
 
  
  0.681
lpxB
Lipid-A-disaccharide synthase, family GT19; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
    0.643
CAZ96608.1
This membrane protein seems involved in the insertion of outer membrane proteins. It has two domains. The C-terminal part, a beta-barrel pore-forming region inserted in the outer membrane, is a Bacterial surface antigen (D15) domain. The N-terminal part, exposed in the periplasm, and involved in gating of the pore and binding of the substrate proteins consists of four Surface antigen variable number repeats; Belongs to the surface antigen D15 family; Signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Family membership.
 
     0.633
lpxD2
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
     0.576
cda1
Cda is a calcium-dependent ATPase. Vanadate strongly inhibits its activity; Belongs to the alkaline phosphatase clan, type I phosphodiesterase family; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; High confidence in function and specificity.
       0.568
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.