STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ94964.1Endonuclease; Protein that consists of an GIY-YIG catalytic domain of unknown function found in the amino terminal region of excinuclease abc subunit c (region 1 of UvrC) and in few other nucleases from bacteria and bacteriophages; Localized in the cytoplasm; Function unclear. (87 aa)    
Predicted Functional Partners:
CAZ96331.1
Adenine-specific DNA methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
  
  
 0.502
CAZ96636.1
Conserved hypothetical protein; Signal peptide cleaved between the residues 28 and 29; Possibly localized in the outer membrane.
  
     0.478
folC
Bifunctional enzyme that converts the folates to polyglutamate derivatives; Folylpolyglutamate synthase (EC 6.3.2.17) is responsible for the ATP-dependent addition of a polyglutamate tail to tetrahydrofolate. Dihydrofolate synthase (EC 6.3.2.12) is reponsible for attaching the first glutamate residue to dihydropteroate to form dihydrofolate. The combined activity leads to the formation of the coenzyme polyglutamated tetrahydropteroate (H4PteGlu(n)), i.e. various tetrahydrofolates (H4folate); Localized in the cytoplasm; High confidence in function and specificity.
       0.458
tolA
TolA, involved in the tonB-independent uptake of proteins, interacts with the TolQ and TolR, cytoplasmic membrane proteins and with the Pal protein (OprL) in the outer membrane. The transport is energized by the proton motive force. The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; TolA is anchored to the cytoplasmic membrane by a single transmembrane spanning segment near the N-terminus, leaving most of the protein exposed to the periplasm; High confidence in function and specificity.
       0.423
tolR
TolR, involved in the tonB-independent uptake of biopolymers, forms a complex with the proteins TolQ. This complex energizes TolA from the potential energy of the ion electrochemical gradient. TolA energized, interacts with the outer membrane protein Pal (OprL). The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; Contains a N-terminal transmembrane helix; Belongs to the exbD/tolR family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.423
tolQ
TolQ, involved in the tonB-independent uptake of biopolymers, forms a complex with the proteins TolR. This complex energizes TolA from the potential energy of the ion electrochemical gradient. TolA energized, interacts with the outer membrane protein Pal (OprL). The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; Contains three transmembrane helices; Belongs to the exbB/tolQ family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.421
rsmI
Methyltransferases; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
  
  
 0.407
CAZ94075.1
Methyltransferases; Enzyme that uses S-AdoMet in the methylation of diverse substrates; Belongs to the UPF0011 family; Localized in the cytoplasm; Specificity unclear.
  
  
 0.407
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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