STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CAZ94969.1Conserved protein belonging to the citrate transporter family, which includes two characterized citrate/proton symporters from Bacillus subtilis. Its exact specificity is unknown. Features eleven transmembrane helices. Localized in the cytoplasmic membrane; Family membership. (455 aa)    
Predicted Functional Partners:
CAZ94970.1
NAD(P)-dependent dehydrogenase distantly related to glutamate dehydrogenase; Localized in the cytoplasm; Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.786
tolQ
TolQ, involved in the tonB-independent uptake of biopolymers, forms a complex with the proteins TolR. This complex energizes TolA from the potential energy of the ion electrochemical gradient. TolA energized, interacts with the outer membrane protein Pal (OprL). The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; Contains three transmembrane helices; Belongs to the exbB/tolQ family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
     
 0.659
tolA
TolA, involved in the tonB-independent uptake of proteins, interacts with the TolQ and TolR, cytoplasmic membrane proteins and with the Pal protein (OprL) in the outer membrane. The transport is energized by the proton motive force. The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; TolA is anchored to the cytoplasmic membrane by a single transmembrane spanning segment near the N-terminus, leaving most of the protein exposed to the periplasm; High confidence in function and specificity.
       0.650
tolR
TolR, involved in the tonB-independent uptake of biopolymers, forms a complex with the proteins TolQ. This complex energizes TolA from the potential energy of the ion electrochemical gradient. TolA energized, interacts with the outer membrane protein Pal (OprL). The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; Contains a N-terminal transmembrane helix; Belongs to the exbD/tolR family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
       0.650
folC
Bifunctional enzyme that converts the folates to polyglutamate derivatives; Folylpolyglutamate synthase (EC 6.3.2.17) is responsible for the ATP-dependent addition of a polyglutamate tail to tetrahydrofolate. Dihydrofolate synthase (EC 6.3.2.12) is reponsible for attaching the first glutamate residue to dihydropteroate to form dihydrofolate. The combined activity leads to the formation of the coenzyme polyglutamated tetrahydropteroate (H4PteGlu(n)), i.e. various tetrahydrofolates (H4folate); Localized in the cytoplasm; High confidence in function and specificity.
     
 0.633
CAZ95599.1
Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership.
 
   
 0.506
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
    0.427
bcdA
Butyryl-CoA dehydrogenase converts the Butanoyl-CoA to 2-butenoyl-CoA. It uses electron transfer flavoprotein (FAD) as its electron acceptor; Localized in the cytoplasm; High confidence in function and specificity.
  
    0.421
CAZ95134.1
Citrate transporter family protein; The exact specificity of this conserved ion transporter is unknown; belongs to the citrate transporter family; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear.
     
 0.416
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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