STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95036.1Peptidase family M23 mainly contains endopeptidases that lyze bacterial cell wall peptidoglycans. One catalytic zinc ion is bound per peptidase molecule. The cation ligands occur in the conserved motifs HXXXD and HXH. The first histidine of the second motif is also involved in the catalysis. Features a transmembrane helix in N-terminus. Localized in the cytoplasmic membrane; Specificity unclear. (325 aa)    
Predicted Functional Partners:
CAZ95037.1
Transcriptional regulator belonging to the MerR family. Contains a N-terminal helix-turn-helix DNA binding motif; Forms a dimer; Localized in the cytoplasm; Specificity unclear.
  
    0.786
CAZ97113.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 26 and 27; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein.
  
   
 0.694
CAZ95827.1
Conserved hypothetical protein belonging to the DUF583 family; Localized in the cytoplasm.
 
   
 0.674
alaS
Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.587
CAZ95038.1
LemA family protein; Conserved protein belonging to the LemA family. LemA contains an amino terminal domain predicted as transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain; Localized in the cytoplasmic membrane; Family membership.
       0.554
CAZ95039.1
Conserved protein belonging to the DUF477 family; Localized in the cytoplasm; Family membership.
       0.554
CAZ95040.1
Conserved protein belonging to the DUF477 family; Contains one C-terminal transmembrane segment; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.553
pbp1A
Penicillin-binding protein 1A, family GT51; Penicillin-binding protein 1A is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane; High confidence in [...]
  
   
 0.546
ftsI
Peptidoglycan synthetase, family GT51; Enzyme essential for the formation of a septum of the murein sacculus. Synthetizes the cross-linked peptidoglycan from the lipid intermediates; Contains in its N-terminal half part a transmembrane segment and an penicillin insensitive transglycosylase domain (formation of linear glycan strands). In its C-terminal half part, a penicillin- sensitive transpeptidase domain (cross-linking of the peptide subunits) and a PASTA domain that binds the beta-lactam stem are present; Belongs to the family 51 of glycosyl transferases (GT51); Except for the cyto [...]
 
   
 0.411
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
   
 0.403
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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