STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO1262Similar to Escherichia coli nucleoid-associated protein YejK SW:NA37_ECOLI (P33920) (334 aa) fasta scores: E(): 0, 79.7% id in 330 aa, and to Vibrio cholerae hypothetical protein VC2039 TR:Q9KQF9 (EMBL:AE004278) (333 aa) fasta scores: E(): 0, 54.4% id in 331 aa. (334 aa)    
Predicted Functional Partners:
YPO1260
Putative membrane protein; Similar to Escherichia coli hypothetical protein YejM SW:YEJM_ECOLI (P33922) (586 aa) fasta scores: E(): 0,63.3% id in 600 aa, and to Vibrio cholerae hypothetical protein VC2041 TR:Q9KQF7 (EMBL:AE004278) (600 aa) fasta scores: E(): 0, 41.9% id in 604 aa.
 
  
 0.895
YPO1261
Similar to Escherichia coli hypothetical protein YejL SW:YEJL_ECOLI (P33921) (75 aa) fasta scores: E(): 5e-21, 80.0% id in 75 aa, and to Vibrio cholerae hypothetical protein VC2040 TR:Q9KQF8 (EMBL:AE004278) (71 aa) fasta scores: E(): 5.7e-12, 54.3% id in 70 aa, and to Haemophilus influenzae hypothetical protein HI0840 SW:YEJL_HAEIN (P44897) (72 aa) fasta scores: E(): 5.5e-09,42.9% id in 70 aa; Belongs to the UPF0352 family.
 
  
 0.786
YPO2564
Similar to Escherichia coli hypothetical protein B2295 TR:P77496 (EMBL:AE000318) (151 aa) fasta scores: E(): 0, 70.2% id in 151 aa, and to Vibrio cholerae hypothetical protein VC1099 TR:Q9KT06 (EMBL:AE004191) (152 aa) fasta scores: E(): 1.7e-24, 47.3% id in 146 aa.
  
     0.685
rlmM
Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
  
    0.568
YPO1265
Putative DEAD box helicase family protein; Similar to Escherichia coli hypothetical protein YejH SW:YEJH_ECOLI (P33919) (586 aa) fasta scores: E(): 0,78.4% id in 584 aa, and to Lactobacillus casei bacteriophage A2 hypothetical protein TR:Q9T0Y3 (EMBL:AJ251789) (455 aa) fasta scores: E(): 7.7e-10, 27.9% id in 373 aa, and to Vibrio cholerae helicase-related protein VC1636 TR:Q9KRK4 (EMBL:AE004241) (657 aa) fasta scores: E(): 0, 59.8% id in 572 aa.
  
   
 0.548
YPO0950
Similar to Escherichia coli hypothetical protein YggL SW:YGGL_ECOLI (P38521) (108 aa) fasta scores: E(): 0,78.7% id in 108 aa, and to Haemophilus influenzae hypothetical protein HI0341 SW:YGGL_HAEIN (P44649) (114 aa) fasta scores: E(): 1.7e-27, 59.3% id in 108 aa.
  
    0.547
seqA
Putative negative regulator of replication initiation; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
    0.490
matP
Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.489
metJ
Transcriptional repressor protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
    0.479
tnp-20
Similar to Salmonella typhimurium, and Salmonella typhi transposase for insertion sequence IS200 TnpA SW:T200_SALTY (Q57334) (152 aa) fasta scores: E(): 0, 94.1% id in 152 aa. Identical to the Yersinia pseudotuberculosis IS1541-like element transposase Tnp TR:Q9X9F5 (EMBL:AJ238014) (152 aa) fasta scores: E(): 0, 100.0% id in 152 aa.
       0.443
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.