STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmIConserved hypothetical protein; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. (396 aa)    
Predicted Functional Partners:
hspQ
Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.
  
    0.693
YPO1446
Putative acylphosphatase; Similar to Cavia porcellus skeletal muscle acylphosphatase AcyP SW:ACYM_CAVPO (P35744) (98 aa) fasta scores: E(): 1.2e-05, 34.9% id in 86 aa, and to Escherichia coli putative acylphosphatase YccX SW:ACYP_ECOLI (P75877) (92 aa) fasta scores: E(): 5.3e-21, 62.0% id in 92 aa.
     
 0.611
rlmL
Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
  
  
0.462
hdfR
LysR-family transcriptional regulatory protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
      
 0.432
ymfC
Putative pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
 
 
 0.430
asuC
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.426
dksA
DnaK suppressor protein homologue; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.
     
 0.416
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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