STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speDS-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
 
 0.999
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.974
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.624
YPO0269
Similar to Salmonella typhimurium secretion system apparatus protein SsaQ SW:SSAQ_SALTY (P74860) (322 aa) fasta scores: E(): 1.1e-20, 26.3% id in 285 aa.
   
    0.616
fliN
Flagellar switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
    0.616
flaN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
    0.616
pndA
Xanthosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.572
ypeI
N-acylhomoserine lactone synthase YpeI; Previously sequenced as Yersinia pestis,quorum-sensing signal generator, N-acylhomoserine lactone synthase, YpeI TR:Q9RH44 (EMBL:AF071401) (214 aa) fasta scores: E(): 0, 100.0% id in 214 aa. Similar to Erwinia chrysanthemi autoinducer synthesis protein ExpI SW:EXPI_ERWCH (Q47187) (212 aa) fasta scores: E(): 0, 54.8% id in 210 aa. Similar to YPO0984 (46.9% identity in 213 aa overlap).
   
 
  0.569
argM
Succinylornithine aminotransferase; Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
     
 0.511
yacC
Putative exported protein; Similar to Escherichia coli hypothetical 12.8 kDa protein in speE-gcd intergenic region precursor YacC SW:YACC_ECOLI (P23838) (115 aa) fasta scores: E(): 8.1e-33,71.2% id in 111 aa, and to Klebsiella pneumoniae pullulanase secretion protein PulS precursor SW:PULS_KLEPN (P20440) (125 aa) fasta scores: E(): 0.0052, 28.6% id in 105 aa, and to Erwinia chrysanthemi OutS protein precursor SW:OUTS_ERWCH (Q01567) (133 aa) fasta scores: E(): 0.0055,31.3% id in 96 aa.
 
    0.484
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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