Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADQ05862.1PFAM: protein of unknown function DUF72; KEGG: ate:Athe_0100 protein of unknown function DUF72. (247 aa)    
Predicted Functional Partners:
ADQ05863.1
KEGG: ate:Athe_0101 monosaccharide-transporting ATPase.
       0.645
ADQ05864.1
KEGG: ate:Athe_0102 two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver.
       0.598
ADQ05865.1
KEGG: ate:Athe_0103 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein.
       0.598
ADQ05866.1
KEGG: ate:Athe_0104 hypothetical protein.
       0.586
ADQ07783.1
KEGG: ate:Athe_0585 phosphoribosyltransferase.
 
     0.509
ADQ06860.1
PFAM: Circadian clock protein KaiC central region; KEGG: ate:Athe_1613 putative circadian clock protein, KaiC.
 
     0.411
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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