Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ05930.1KEGG: ate:Athe_2353 hypothetical protein. (667 aa)    
Predicted Functional Partners:
ADQ07682.1
KEGG: ate:Athe_0697 hypothetical protein.
  
     0.678
ADQ05931.1
KEGG: gyc:GYMC61_1695 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
       0.550
ADQ05932.1
KEGG: gyc:GYMC61_1696 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
       0.550
ADQ07675.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain protein; KEGG: ate:Athe_0704 transketolase central region.
  
     0.503
ADQ05959.1
PFAM: lipolytic protein G-D-S-L family; KEGG: ate:Athe_2325 lipolytic protein G-D-S-L family.
  
     0.502
ADQ05898.1
PFAM: glycoside hydrolase family 28; KEGG: ate:Athe_2380 galacturan 1,4-alpha-galacturonidase; Belongs to the glycosyl hydrolase 28 family.
  
     0.491
ADQ07680.1
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ate:Athe_0699 alcohol dehydrogenase zinc-binding domain protein.
  
     0.412
ADQ05897.1
PFAM: glycosyl hydrolase family 88; KEGG: csc:Csac_0360 glycosy hydrolase family protein.
  
     0.407
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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