Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ06017.1KEGG: ate:Athe_2581 hypothetical protein. (996 aa)    
Predicted Functional Partners:
ADQ06016.1
PFAM: cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; KEGG: ate:Athe_2582 methionine synthase.
 
     0.761
ADQ06018.1
PFAM: class II aldolase/adducin family protein; KEGG: csc:Csac_0425 class II aldolase/adducin family protein.
       0.689
ADQ07997.1
PFAM: major facilitator superfamily MFS_1; KEGG: ate:Athe_0342 major facilitator superfamily MFS_1.
  
     0.657
ADQ06585.1
KEGG: ate:Athe_1930 hypothetical protein.
  
     0.644
ADQ05908.1
KEGG: csc:Csac_0363 hypothetical protein.
  
     0.633
ADQ07808.1
PFAM: lipolytic protein G-D-S-L family; KEGG: ate:Athe_0553 lipolytic protein G-D-S-L family.
  
 
 0.598
ADQ08066.1
PFAM: glycoside hydrolase family 5; KEGG: ate:Athe_0234 glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
 
 0.598
ADQ08137.1
PFAM: extracellular solute-binding protein family 1; KEGG: ate:Athe_0181 extracellular solute-binding protein family 1.
  
     0.592
ADQ06025.1
KEGG: csc:Csac_0432 hypothetical protein; Belongs to the uroporphyrinogen decarboxylase family.
  
    0.573
ADQ06586.1
PFAM: protein of unknown function DUF1362; KEGG: csc:Csac_1017 hypothetical protein.
 
     0.560
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
Server load: low (12%) [HD]