STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ06069.1PFAM: TRAG family protein; KEGG: ate:Athe_2519 TraG family protein. (625 aa)    
Predicted Functional Partners:
ADQ06060.1
SMART: AAA ATPase; KEGG: ate:Athe_2528 AAA ATPase.
 
  
 0.835
ADQ06168.1
KEGG: ate:Athe_2472 HNH endonuclease; PFAM: HNH endonuclease; SMART: HNH nuclease.
 
 
 
 0.790
ADQ06070.1
KEGG: ddi:DDB_0191431 spore coat protein SP75.
       0.773
ADQ06068.1
KEGG: ate:Athe_2520 hypothetical protein.
       0.751
ADQ06186.1
PFAM: zinc finger CHC2-family protein; KEGG: ate:Athe_2405 hypothetical protein.
 
     0.748
ADQ06092.1
KEGG: mar:MAE_11230 hypothetical protein.
   
 
 0.741
ADQ06072.1
PFAM: RNA binding S1 domain protein; KEGG: ate:Athe_2517 RNA binding S1 domain protein.
 
     0.679
ADQ07212.1
PFAM: Patatin; KEGG: ate:Athe_1230 patatin.
    
   0.648
ADQ06071.1
PFAM: Radical SAM domain protein; KEGG: ate:Athe_2518 radical SAM domain protein.
       0.603
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.566
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.