Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ06614.1PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: ate:Athe_1899 cytochrome c biogenesis protein transmembrane region. (215 aa)    
Predicted Functional Partners:
ADQ06615.1
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: ate:Athe_1898 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
  
 0.988
ADQ06612.1
PFAM: PemK family protein; KEGG: ate:Athe_1901 transcriptional modulator of MazE/toxin, MazF.
     
 0.741
ADQ06611.1
KEGG: ate:Athe_1902 hypothetical protein.
       0.729
ADQ06613.1
KEGG: ate:Athe_1900 hypothetical protein.
       0.729
ADQ06616.1
PFAM: glycine cleavage H-protein; KEGG: ate:Athe_1897 glycine cleavage H-protein.
       0.582
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.495
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.489
ADQ06617.1
PFAM: periplasmic binding protein; KEGG: ate:Athe_1896 periplasmic binding protein.
  
    0.480
ADQ06609.1
KEGG: ate:Athe_1904 hypothetical protein.
       0.476
ADQ06619.1
KEGG: ate:Athe_1894 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
    0.446
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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