Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ06626.1TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: csc:Csac_1061 twitching motility protein; SMART: AAA ATPase. (351 aa)    
Predicted Functional Partners:
ADQ06627.1
PFAM: Type II secretion system F domain; KEGG: ate:Athe_1882 type II secretion system protein.
 
  
 0.962
ADQ06629.1
KEGG: csc:Csac_1065 peptidase A24A domain-containing protein; PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV.
 
   
 0.942
ADQ06625.1
KEGG: csc:Csac_1060 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase.
 
  
0.862
ADQ06628.1
KEGG: ate:Athe_1880 hypothetical protein.
 
  
 0.804
ADQ06633.1
KEGG: ate:Athe_1875 Tfp pilus assembly protein ATPase PilM-like protein.
 
   
 0.722
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
     
 0.668
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.652
ADQ06623.1
TIGRFAM: HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: ate:Athe_1890 HAD superfamily (subfamily IIIA) phosphatase, TIGR01668.
       0.650
ADQ06635.1
KEGG: ate:Athe_1873 hypothetical protein.
  
  
 0.642
ADQ06631.1
KEGG: ate:Athe_1877 hypothetical protein.
     
 0.606
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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