Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ06673.1Transcriptional regulator, CdaR; PFAM: helix-turn-helix Fis-type; KEGG: ate:Athe_1802 transcriptional regulator, CdaR. (364 aa)    
Predicted Functional Partners:
ADQ06675.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.777
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.776
ADQ07162.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; KEGG: ate:Athe_1281 hypothetical protein.
  
     0.742
ADQ06676.1
PFAM: Peptidase M23; KEGG: ate:Athe_1799 peptidase M23.
       0.667
ADQ07835.1
KEGG: ate:Athe_0528 hypothetical protein.
  
     0.603
ADQ06677.1
TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; KEGG: ate:Athe_1798 carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family.
       0.591
ADQ06672.1
KEGG: csc:Csac_2346 ABC transporter related; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase.
       0.588
ADQ06678.1
KEGG: ate:Athe_1797 PDZ/DHR/GLGF domain protein.
       0.553
ADQ06834.1
KEGG: ate:Athe_1640 hypothetical protein.
  
     0.546
ADQ06922.1
PFAM: Domain of unknown function DUF1858; KEGG: ate:Athe_1535 domain of unknown function DUF1858.
  
     0.512
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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