Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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ADQ06677.1TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; KEGG: ate:Athe_1798 carboxyl-terminal protease; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family. (397 aa)    
Predicted Functional Partners:
ADQ06676.1
PFAM: Peptidase M23; KEGG: ate:Athe_1799 peptidase M23.
 
  
 0.829
ADQ06678.1
KEGG: ate:Athe_1797 PDZ/DHR/GLGF domain protein.
  
  
 0.810
ADQ06675.1
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
     0.730
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.688
ADQ06673.1
Transcriptional regulator, CdaR; PFAM: helix-turn-helix Fis-type; KEGG: ate:Athe_1802 transcriptional regulator, CdaR.
       0.591
ADQ06666.1
KEGG: ate:Athe_1809 membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50.
 
  
 0.544
ADQ08285.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold domain protein; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
   
 
 0.483
ADQ06621.1
KEGG: ate:Athe_1892 NLP/P60 protein; PFAM: NLP/P60 protein; SH3 type 3 domain protein; SMART: SH3 domain protein.
    
 
 0.462
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
    0.408
ADQ06220.1
KEGG: ate:Athe_2280 heavy metal translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; copper ion binding protein; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase.
 
   
 0.401
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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