STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkKEGG: ate:Athe_1325 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; shikimate kinase. (226 aa)    
Predicted Functional Partners:
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
  
 0.967
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.933
ADQ07119.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
      0.932
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.929
ADQ07831.1
SMART: AAA ATPase; KEGG: ate:Athe_0531 AAA ATPase.
  
 
 0.925
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
      0.907
ADQ07732.1
PFAM: CMP/dCMP deaminase zinc-binding; KEGG: ate:Athe_0634 CMP/dCMP deaminase zinc-binding.
    
  0.902
ADQ07117.1
TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: ate:Athe_1326 phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
     
 0.871
ADQ07551.1
KEGG: ate:Athe_0844 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase.
 
  
 0.856
ADQ07120.1
PFAM: HutP family protein; KEGG: ate:Athe_1323 HutP family protein.
       0.827
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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