STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (679 aa)    
Predicted Functional Partners:
ADQ07598.1
Putative transcriptional regulator; PFAM: AAA-4 family protein; KEGG: ate:Athe_0799 putative transcriptional regulator.
     
  0.900
ADQ07219.1
DAK2 domain fusion protein YloV; KEGG: ate:Athe_1223 Dak phosphatase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: Dak phosphatase.
  
    0.868
ADQ07220.1
PFAM: protein of unknown function DUF322; KEGG: ate:Athe_1222 protein of unknown function DUF322.
       0.808
ADQ07223.1
KEGG: ate:Athe_1219 RNA methylase, NOL1/NOP2/sun family; TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein.
  
    0.759
ADQ07221.1
Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
       0.705
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.687
ADQ07222.1
KEGG: ate:Athe_1220 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family.
       0.655
ADQ07217.1
PFAM: small acid-soluble spore protein alpha/beta type; KEGG: ate:Athe_1225 small acid-soluble spore protein alpha/beta type.
       0.635
ADQ07224.1
KEGG: ate:Athe_1218 protein of unknown function Met10; PFAM: RNA cap guanine-N2 methyltransferase; SMART: PUA domain containing protein.
  
    0.614
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
  
 0.601
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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