Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ07219.1DAK2 domain fusion protein YloV; KEGG: ate:Athe_1223 Dak phosphatase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: Dak phosphatase. (546 aa)    
Predicted Functional Partners:
ADQ06366.1
KEGG: ate:Athe_2132 DegV family protein; TIGRFAM: degV family protein; PFAM: DegV family protein.
 
 0.996
ADQ07220.1
PFAM: protein of unknown function DUF322; KEGG: ate:Athe_1222 protein of unknown function DUF322.
 
  
 0.991
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
    0.861
ADQ07221.1
Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
 
     0.758
ADQ07222.1
KEGG: ate:Athe_1220 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family.
 
     0.690
ADQ07223.1
KEGG: ate:Athe_1219 RNA methylase, NOL1/NOP2/sun family; TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein.
       0.668
ADQ07224.1
KEGG: ate:Athe_1218 protein of unknown function Met10; PFAM: RNA cap guanine-N2 methyltransferase; SMART: PUA domain containing protein.
       0.572
ADQ07214.1
KEGG: ate:Athe_1228 hypothetical protein.
 
     0.571
ADQ07217.1
PFAM: small acid-soluble spore protein alpha/beta type; KEGG: ate:Athe_1225 small acid-soluble spore protein alpha/beta type.
       0.561
ADQ07216.1
Methyltransferase; KEGG: ate:Athe_1226 methyltransferase; TIGRFAM: methyltransferase; PFAM: conserved hypothetical protein.
 
     0.560
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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