STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07319.1KEGG: ate:Athe_1130 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: Cache type 2 domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; SMART: chemotaxis sensory transducer. (571 aa)    
Predicted Functional Partners:
ADQ07562.1
PFAM: MCP methyltransferase CheR-type; KEGG: ate:Athe_0833 MCP methyltransferase, CheR-type; SMART: MCP methyltransferase CheR-type.
 
 0.983
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.983
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.983
ADQ06348.1
KEGG: ate:Athe_2149 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein.
 
 0.980
ADQ06705.1
KEGG: ate:Athe_1770 CheA signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; P2 response regulator binding domain protein; CheW domain protein; SMART: ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein.
 
 0.980
ADQ06349.1
KEGG: ate:Athe_2148 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.978
ADQ06391.1
KEGG: ate:Athe_2102 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.978
ADQ06706.1
KEGG: ate:Athe_1769 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein.
 
 0.978
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.975
ADQ08039.1
PFAM: chemotaxis sensory transducer; KEGG: cbe:Cbei_3486 methyl-accepting chemotaxis sensory transducer.
  
     0.773
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.