node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADQ07646.1 | ADQ07647.1 | Calhy_1936 | Calhy_1937 | KEGG: ate:Athe_0754 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11. | 0.615 |
ADQ07646.1 | ADQ07650.1 | Calhy_1936 | Calhy_1940 | KEGG: ate:Athe_0754 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | PFAM: protein of unknown function DUF512; KEGG: ate:Athe_0750 protein of unknown function DUF512. | 0.576 |
ADQ07646.1 | hslO | Calhy_1936 | Calhy_1935 | KEGG: ate:Athe_0754 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.683 |
ADQ07647.1 | ADQ07646.1 | Calhy_1937 | Calhy_1936 | PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11. | KEGG: ate:Athe_0754 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | 0.615 |
ADQ07647.1 | ADQ07650.1 | Calhy_1937 | Calhy_1940 | PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11. | PFAM: protein of unknown function DUF512; KEGG: ate:Athe_0750 protein of unknown function DUF512. | 0.782 |
ADQ07647.1 | hslO | Calhy_1937 | Calhy_1935 | PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11. | Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.553 |
ADQ07650.1 | ADQ07646.1 | Calhy_1940 | Calhy_1936 | PFAM: protein of unknown function DUF512; KEGG: ate:Athe_0750 protein of unknown function DUF512. | KEGG: ate:Athe_0754 cold-shock DNA-binding domain protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein. | 0.576 |
ADQ07650.1 | ADQ07647.1 | Calhy_1940 | Calhy_1937 | PFAM: protein of unknown function DUF512; KEGG: ate:Athe_0750 protein of unknown function DUF512. | PFAM: Methyltransferase type 12; KEGG: ate:Athe_0753 methyltransferase type 11. | 0.782 |
ADQ07650.1 | hslO | Calhy_1940 | Calhy_1935 | PFAM: protein of unknown function DUF512; KEGG: ate:Athe_0750 protein of unknown function DUF512. | Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.529 |
ADQ07717.1 | grpE | Calhy_2007 | Calhy_1185 | KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.502 |
ADQ07717.1 | hslO | Calhy_2007 | Calhy_1935 | KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein. | Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.772 |
ADQ07717.1 | hslU | Calhy_2007 | Calhy_0578 | KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.537 |
ADQ07717.1 | hslV | Calhy_2007 | Calhy_0577 | KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein. | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.610 |
groL | grpE | Calhy_0619 | Calhy_1185 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.989 |
groL | hslO | Calhy_0619 | Calhy_1935 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. | 0.645 |
groL | hslU | Calhy_0619 | Calhy_0578 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.822 |
groL | hslV | Calhy_0619 | Calhy_0577 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.779 |
groL | lon | Calhy_0619 | Calhy_1772 | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.772 |
grpE | ADQ07717.1 | Calhy_1185 | Calhy_2007 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | KEGG: ate:Athe_0649 RNA-binding S4 domain protein; PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein. | 0.502 |
grpE | groL | Calhy_1185 | Calhy_0619 | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.989 |