Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ07675.1PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain protein; KEGG: ate:Athe_0704 transketolase central region. (823 aa)    
Predicted Functional Partners:
ADQ07676.1
KEGG: ate:Athe_0703 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.
 
 0.999
ADQ07677.1
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: ate:Athe_0702 catalytic domain of components of various dehydrogenase complexes.
 
 0.999
ADQ07490.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ate:Athe_0931 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.996
ADQ08089.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tex:Teth514_0146 NADH:flavin oxidoreductase/NADH oxidase.
  
 0.996
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.976
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 0.969
ADQ06768.1
KEGG: ate:Athe_1709 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 0.962
ADQ07407.1
KEGG: ate:Athe_1044 protein serine/threonine phosphatase; PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein.
  
 0.956
ADQ08036.1
KEGG: ate:Athe_2764 protein of unknown function UPF0236.
  
 0.956
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.953
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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