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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADQ07680.1PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ate:Athe_0699 alcohol dehydrogenase zinc-binding domain protein. (421 aa)    
Predicted Functional Partners:
ADQ07681.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0698 short-chain dehydrogenase/reductase SDR.
 
 
 0.962
ADQ07675.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain protein; KEGG: ate:Athe_0704 transketolase central region.
 
  
 0.907
ADQ07682.1
KEGG: ate:Athe_0697 hypothetical protein.
 
     0.837
ADQ07677.1
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: ate:Athe_0702 catalytic domain of components of various dehydrogenase complexes.
 
  
 0.760
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
   
 0.694
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
     
 0.660
ADQ07676.1
KEGG: ate:Athe_0703 dihydrolipoamide dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region.
 
  
 0.559
ADQ07964.1
PFAM: Radical SAM domain protein; KEGG: ate:Athe_0390 radical SAM domain protein.
 
     0.483
ADQ06298.1
PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; KEGG: ate:Athe_2206 alcohol dehydrogenase GroES domain protein.
  
     0.436
pgk
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.431
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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