STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07681.1PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0698 short-chain dehydrogenase/reductase SDR. (259 aa)    
Predicted Functional Partners:
ADQ07680.1
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ate:Athe_0699 alcohol dehydrogenase zinc-binding domain protein.
 
 
 0.962
ADQ06378.1
PFAM: PfkB domain protein; KEGG: csc:Csac_1312 ribokinase-like domain-containing protein.
  
 0.910
ADQ06420.1
PFAM: PfkB domain protein; KEGG: ate:Athe_2118 PfkB domain protein.
  
 0.910
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.909
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.909
ADQ07747.1
TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS).
  
 
 0.908
ADQ07682.1
KEGG: ate:Athe_0697 hypothetical protein.
 
     0.811
ADQ07675.1
PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain protein; KEGG: ate:Athe_0704 transketolase central region.
 
 
 0.758
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.642
ADQ07902.1
PFAM: alpha-L-rhamnosidase; alpha-L-rhamnosidase domain protein; KEGG: pjd:Pjdr2_2986 alpha-L-rhamnosidase.
   
 
 0.597
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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