| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADQ06550.1 | ADQ06552.1 | Calhy_0814 | Calhy_0816 | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.949 |
| ADQ06550.1 | ADQ07711.1 | Calhy_0814 | Calhy_2001 | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.652 |
| ADQ06550.1 | ADQ08001.1 | Calhy_0814 | Calhy_2297 | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | 0.724 |
| ADQ06550.1 | hisI | Calhy_0814 | Calhy_1264 | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | KEGG: ate:Athe_1472 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family. | 0.641 |
| ADQ06550.1 | thrB | Calhy_0814 | Calhy_0815 | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.841 |
| ADQ06552.1 | ADQ06550.1 | Calhy_0816 | Calhy_0814 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.949 |
| ADQ06552.1 | ADQ07317.1 | Calhy_0816 | Calhy_1602 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | 0.790 |
| ADQ06552.1 | ADQ07711.1 | Calhy_0816 | Calhy_2001 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.967 |
| ADQ06552.1 | ADQ08001.1 | Calhy_0816 | Calhy_2297 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | 0.963 |
| ADQ06552.1 | hisI | Calhy_0816 | Calhy_1264 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | KEGG: ate:Athe_1472 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family. | 0.496 |
| ADQ06552.1 | ilvC | Calhy_0816 | Calhy_2166 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.407 |
| ADQ06552.1 | thrB | Calhy_0816 | Calhy_0815 | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.999 |
| ADQ07317.1 | ADQ06552.1 | Calhy_1602 | Calhy_0816 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.790 |
| ADQ07317.1 | ADQ07711.1 | Calhy_1602 | Calhy_2001 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.652 |
| ADQ07317.1 | ADQ08001.1 | Calhy_1602 | Calhy_2297 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; KEGG: ate:Athe_0325 homocysteine S-methyltransferase. | 0.724 |
| ADQ07317.1 | hisI | Calhy_1602 | Calhy_1264 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | KEGG: ate:Athe_1472 phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; In the N-terminal section; belongs to the PRA-CH family. | 0.641 |
| ADQ07317.1 | thrB | Calhy_1602 | Calhy_0815 | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.592 |
| ADQ07711.1 | ADQ06550.1 | Calhy_2001 | Calhy_0814 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | KEGG: ate:Athe_1961 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.652 |
| ADQ07711.1 | ADQ06552.1 | Calhy_2001 | Calhy_0816 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: ate:Athe_1959 homoserine dehydrogenase. | 0.967 |
| ADQ07711.1 | ADQ07317.1 | Calhy_2001 | Calhy_1602 | TIGRFAM: threonine synthase; KEGG: ate:Athe_0655 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: amino acid-binding ACT domain protein; KEGG: ate:Athe_1132 amino acid-binding ACT domain protein. | 0.652 |