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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07720.1KEGG: ate:Athe_0646 hypothetical protein. (94 aa)    
Predicted Functional Partners:
ADQ07451.1
PFAM: Sporulation stage III protein AE; KEGG: ate:Athe_0994 hypothetical protein.
  
    0.929
ADQ07439.1
KEGG: ate:Athe_1006 transcriptional regulator, AbrB family; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein.
  
  
 0.889
ADQ05983.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.880
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.879
ADQ06558.1
PFAM: Sporulation stage II protein R; KEGG: ate:Athe_1953 hypothetical protein.
  
   
 0.874
ADQ06686.1
KEGG: ate:Athe_1789 stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein.
  
  
 0.869
ADQ07611.1
Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.856
ADQ07455.1
SMART: AAA ATPase; KEGG: ate:Athe_0990 AAA ATPase.
  
   
 0.855
ADQ08099.1
Protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; KEGG: ate:Athe_0217 protein serine/threonine phosphatase; SMART: protein phosphatase 2C domain protein.
  
   
 0.854
ADQ07106.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.852
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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