Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07841.1PFAM: pyruvate carboxyltransferase; KEGG: csc:Csac_2456 pyruvate carboxyltransferase. (329 aa)    
Predicted Functional Partners:
ADQ06768.1
KEGG: ate:Athe_1709 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.910
ADQ06769.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ate:Athe_1708 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.909
ADQ07677.1
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; KEGG: ate:Athe_0702 catalytic domain of components of various dehydrogenase complexes.
    
 0.908
ADQ06282.1
PFAM: pyruvate carboxyltransferase; KEGG: ate:Athe_2226 pyruvate carboxyltransferase.
  
  
 
0.906
ADQ07859.1
PFAM: pyruvate carboxyltransferase; KEGG: ate:Athe_0518 pyruvate carboxyltransferase.
  
  
 
0.906
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.903
ADQ07354.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: ate:Athe_1097 thiamine pyrophosphate protein domain protein TPP-binding.
   
 
 0.902
ADQ07355.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_1096 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
   
 
 0.902
ADQ07524.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: csc:Csac_1461 thiamine pyrophosphate binding domain-containing protein.
   
 
 0.902
ADQ07525.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ate:Athe_0876 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
   
 
 0.902
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.