Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07855.1KEGG: csc:Csac_2477 ammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter. (448 aa)    
Predicted Functional Partners:
ADQ07854.1
PFAM: nitrogen regulatory protein P-II; KEGG: csc:Csac_2476 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 0.993
ADQ07851.1
PFAM: nitrogen regulatory protein P-II; KEGG: csc:Csac_2464 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.864
ADQ07852.1
PFAM: nitrogen regulatory protein P-II; KEGG: csc:Csac_2465 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.853
ADQ06426.1
PFAM: nitrogen regulatory protein P-II; KEGG: csc:Csac_1345 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.825
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
  
  
 0.573
ADQ07923.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: ate:Athe_0447 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
 
      0.532
ADQ06278.1
TIGRFAM: diguanylate cyclase; PFAM: EAL domain protein; GGDEF domain containing protein; KEGG: ate:Athe_2238 diguanylate cyclase/phosphodiesterase; SMART: EAL domain protein; GGDEF domain containing protein.
 
    
 0.527
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.522
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.461
ADQ08285.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold domain protein; PAS fold-3 domain protein; KEGG: ate:Athe_2740 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); SMART: EAL domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS domain containing protein; PAC repeat-containing protein.
    
 0.452
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.