Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ07867.1KEGG: ate:Athe_0510 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region. (185 aa)    
Predicted Functional Partners:
ADQ08291.1
TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; KEGG: ate:Athe_2746 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
 0.999
ADQ07389.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ate:Athe_1062 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
 
 
 0.981
argH
KEGG: ate:Athe_1248 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
    
 0.817
ADQ07321.1
PFAM: aminotransferase class I and II; KEGG: ate:Athe_1128 aminotransferase class I and II.
     
 0.800
ADQ07784.1
Arylformamidase; KEGG: ate:Athe_0573 cyclase family protein; PFAM: cyclase family protein.
     
  0.800
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.781
ADQ07866.1
PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ate:Athe_0511 Orn/Lys/Arg decarboxylase major region.
       0.781
ADQ07864.1
PFAM: protein of unknown function DUF970; KEGG: ate:Athe_0513 protein of unknown function DUF970.
       0.601
ADQ07258.1
PFAM: FAD dependent oxidoreductase; KEGG: csc:Csac_1640 adenylylsulfate reductase subunit alpha.
  
  
 0.586
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
  
 0.583
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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