Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ07877.1PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0501 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)    
Predicted Functional Partners:
ADQ07608.1
PFAM: AMP-dependent synthetase and ligase; KEGG: ate:Athe_0789 AMP-dependent synthetase and ligase.
  
 
 0.811
ADQ06255.1
KEGG: csc:Csac_0698 hypothetical protein.
 
 
 0.638
ADQ07876.1
KEGG: ate:Athe_0502 acetolactate synthase, large subunit, biosynthetic type; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding.
     
 0.498
ADQ07878.1
Addiction module toxin, Txe/YoeB family; KEGG: tpd:Teth39_1581 addiction module antitoxin; TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: plasmid stabilization system.
       0.489
ADQ07879.1
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.489
ADQ07505.1
KEGG: ate:Athe_0895 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
  
   
 0.462
ADQ08089.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tex:Teth514_0146 NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.439
ADQ07881.1
PFAM: amidohydrolase 2; KEGG: csc:Csac_1139 amidohydrolase 2.
 
     0.433
ADQ07681.1
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0698 short-chain dehydrogenase/reductase SDR.
 
 
0.429
ADQ07880.1
KEGG: ate:Athe_0500 beta-lactamase domain protein.
       0.428
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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