close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07895.1PFAM: extracellular solute-binding protein family 1; KEGG: dth:DICTH_0055 extracellular solute-binding protein. (433 aa)    
Predicted Functional Partners:
ADQ07893.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dtu:Dtur_0550 binding-protein-dependent transport systems inner membrane component.
 
  0.991
ADQ07903.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: csc:Csac_1104 response regulator receiver protein.
 
  0.951
ADQ07894.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dth:DICTH_0056 multiple sugar-binding transport system permease.
 
   0.926
ADQ07892.1
Glycosyl hydrolase family 32 domain protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
     0.665
ADQ07891.1
Alpha-galactosidase; KEGG: ate:Athe_0468 glycoside hydrolase clan GH-D; PFAM: glycoside hydrolase clan GH-D.
 
  
 0.602
ADQ07896.1
Transcriptional regulator, LacI family; KEGG: dth:DICTH_0059 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
 
    0.544
ADQ06672.1
KEGG: csc:Csac_2346 ABC transporter related; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase.
  
 
 0.499
ADQ07897.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
       0.465
ADQ06410.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: pjd:Pjdr2_5506 binding-protein-dependent transport systems inner membrane component.
  
   0.448
ADQ06036.1
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ate:Athe_2552 binding-protein-dependent transport systems inner membrane component.
  
   0.446
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.