Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADQ07896.1Transcriptional regulator, LacI family; KEGG: dth:DICTH_0059 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI. (325 aa)    
Predicted Functional Partners:
ADQ07897.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
       0.773
ADQ07898.1
KEGG: csc:Csac_1116 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase.
       0.705
ADQ07899.1
PFAM: aldo/keto reductase; KEGG: ate:Athe_0465 aldo/keto reductase.
       0.705
ADQ06280.1
Transcriptional regulator, GntR family with LacI sensor; KEGG: csc:Csac_0722 regulatory protein GntR, HTH; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH.
  
     0.572
ADQ07895.1
PFAM: extracellular solute-binding protein family 1; KEGG: dth:DICTH_0055 extracellular solute-binding protein.
 
    0.544
ADQ07892.1
Glycosyl hydrolase family 32 domain protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
 
  
 0.461
ADQ07900.1
SNF2-related protein; KEGG: ate:Athe_0464 non-specific serine/threonine protein kinase; PFAM: SNF2-related protein; SNF2 helicase associated domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
       0.420
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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