Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ07898.1KEGG: csc:Csac_1116 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase. (586 aa)    
Predicted Functional Partners:
ADQ07899.1
PFAM: aldo/keto reductase; KEGG: ate:Athe_0465 aldo/keto reductase.
       0.781
ADQ07897.1
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
       0.711
ADQ07896.1
Transcriptional regulator, LacI family; KEGG: dth:DICTH_0059 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
       0.705
ADQ07505.1
KEGG: ate:Athe_0895 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
  
0.545
ADQ07900.1
SNF2-related protein; KEGG: ate:Athe_0464 non-specific serine/threonine protein kinase; PFAM: SNF2-related protein; SNF2 helicase associated domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
   
   0.490
pgk
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.475
ADQ06308.1
KEGG: ate:Athe_2191 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    
0.441
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.436
ADQ07895.1
PFAM: extracellular solute-binding protein family 1; KEGG: dth:DICTH_0055 extracellular solute-binding protein.
       0.429
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
  
   0.420
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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