Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ07907.1GntR domain protein; KEGG: tex:Teth514_0600 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH. (238 aa)    
Predicted Functional Partners:
ADQ07906.1
PFAM: dihydrodipicolinate synthetase; KEGG: tsi:TSIB_1436 putative dihidrodipicolinate synthase; Belongs to the DapA family.
     
 0.736
dapA-2
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.573
ADQ06697.1
KEGG: ate:Athe_1778 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
  
  
 0.503
ADQ05892.1
KEGG: ate:Athe_2387 transcriptional regulator, IclR family; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR.
 
  
 0.458
ADQ08089.1
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tex:Teth514_0146 NADH:flavin oxidoreductase/NADH oxidase.
  
  
 0.458
ADQ07905.1
PFAM: extracellular solute-binding protein family 1; KEGG: pjd:Pjdr2_5098 extracellular solute-binding protein family 1.
       0.447
ADQ06242.1
KEGG: tpd:Teth39_1975 IclR family transcriptional regulator; PFAM: Transcriptional regulator IclR; regulatory protein IclR; SMART: regulatory protein IclR.
 
  
 0.443
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.437
ADQ07177.1
KEGG: ate:Athe_1266 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region.
  
  
 0.421
ADQ06846.1
KEGG: ate:Athe_1627 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain.
 
  
 0.407
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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