close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ07975.1PFAM: glycosidase related protein; KEGG: csc:Csac_0259 glycosidase, PH1107-related. (297 aa)    
Predicted Functional Partners:
ADQ06850.1
PFAM: glycosyl transferase group 1; KEGG: ate:Athe_1623 glycosyl transferase group 1.
 
    0.781
ADQ06851.1
KEGG: ate:Athe_1622 hypothetical protein.
 
     0.777
ADQ07974.1
KEGG: csc:Csac_0260 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI.
       0.698
ADQ07976.1
PFAM: glycosidase related protein; KEGG: csc:Csac_0258 glycosidase, PH1107-related.
 
    
0.678
ADQ07973.1
PFAM: extracellular solute-binding protein family 5; KEGG: csc:Csac_0261 extracellular solute-binding protein.
       0.415
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
       0.400
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.