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ADQ07983.1Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (254 aa)    
Predicted Functional Partners:
ADQ07982.1
PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: csc:Csac_0252 thiamine biosynthesis protein ThiH.
 
 0.998
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.997
thiC
KEGG: csc:Csac_0255 thiamine biosynthesis protein ThiC; TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC.
 
  
 0.988
ADQ08153.1
PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: ate:Athe_0169 biotin and thiamin synthesis associated.
 
 0.983
ADQ07981.1
KEGG: csc:Csac_0253 thiamine biosynthesis protein ThiF; TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein.
 
  
 0.971
ADQ07984.1
KEGG: csc:Csac_0250 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein.
 
 
 0.965
ADQ07978.1
TIGRFAM: phosphomethylpyrimidine kinase; KEGG: ate:Athe_0381 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
 
  
 0.953
dxs
Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.941
thiI
Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.938
ADQ07264.1
KEGG: csc:Csac_1634 thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein.
  
 
 0.867
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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