Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ADQ07987.1PFAM: protein of unknown function UCP033101; KEGG: csc:Csac_0248 hypothetical protein. (260 aa)    
Predicted Functional Partners:
ADQ07986.1
KEGG: ate:Athe_0366 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH.
       0.775
ADQ08000.1
KEGG: ate:Athe_0339 hypothetical protein.
 
     0.560
ADQ06128.1
Hypothetical protein; KEGG: csc:Csac_2638 PKD domain-containing protein.
  
     0.556
ADQ05866.1
KEGG: ate:Athe_0104 hypothetical protein.
  
     0.495
ADQ07245.1
KEGG: ate:Athe_1196 precorrin-2 dehydrogenase.
  
     0.480
hprK
HPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (gluc [...]
       0.445
ADQ05795.1
KEGG: csc:Csac_2571 hypothetical protein.
  
     0.442
ADQ07830.1
KEGG: ate:Athe_0532 hypothetical protein.
  
     0.435
ADQ07990.1
PFAM: YbbR family protein; KEGG: ate:Athe_0362 YbbR family protein.
 
     0.426
ADQ06258.1
KEGG: csc:Csac_0701 hypothetical protein.
  
     0.423
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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