STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ08103.1PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ate:Athe_0213 short-chain dehydrogenase/reductase SDR. (264 aa)    
Predicted Functional Partners:
ADQ08104.1
TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; KEGG: ate:Athe_0212 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
       0.777
ADQ08105.1
KEGG: ate:Athe_0211 hypothetical protein.
       0.773
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.765
ADQ08106.1
TIGRFAM: dihydropteroate synthase; KEGG: ate:Athe_0210 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.
     
 0.696
ADQ08102.1
PFAM: protein of unknown function DUF820; KEGG: ate:Athe_0214 protein of unknown function DUF820.
       0.694
ADQ08108.1
PFAM: protein of unknown function DUF1284; KEGG: ate:Athe_0208 protein of unknown function DUF1284.
       0.661
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 
 0.642
ADQ07292.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.640
ADQ08101.1
KEGG: ate:Athe_0215 hypothetical protein.
       0.614
ADQ07295.1
KEGG: ate:Athe_1155 malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase.
 
 0.601
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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