Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADQ08291.1TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; KEGG: ate:Athe_2746 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region. (278 aa)    
Predicted Functional Partners:
ADQ07867.1
KEGG: ate:Athe_0510 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
 0.999
ADQ07389.1
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: ate:Athe_1062 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
  
 
 0.934
argH
KEGG: ate:Athe_1248 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
    
  0.811
ADQ07321.1
PFAM: aminotransferase class I and II; KEGG: ate:Athe_1128 aminotransferase class I and II.
     
  0.800
ADQ07784.1
Arylformamidase; KEGG: ate:Athe_0573 cyclase family protein; PFAM: cyclase family protein.
     
  0.800
ADQ08290.1
KEGG: ate:Athe_2289 hypothetical protein.
       0.768
ADQ08292.1
PFAM: Colicin V production protein; KEGG: ate:Athe_2747 hypothetical protein.
       0.657
ADQ08293.1
KEGG: ate:Athe_2748 hypothetical protein.
       0.642
ADQ08294.1
TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; KEGG: ate:Athe_2749 putative PAS/PAC sensor protein; SMART: protein phosphatase 2C domain protein.
       0.633
ADQ07258.1
PFAM: FAD dependent oxidoreductase; KEGG: csc:Csac_1640 adenylylsulfate reductase subunit alpha.
  
  
 0.628
Your Current Organism:
Caldicellulosiruptor hydrothermalis
NCBI taxonomy Id: 632292
Other names: C. hydrothermalis 108, Caldicellulosiruptor hydrothermalis 108, Caldicellulosiruptor hydrothermalis DSM 18901, Caldicellulosiruptor hydrothermalis str. 108, Caldicellulosiruptor hydrothermalis strain 108
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