STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADQ40166.1Hypothetical protein; Manually curated; KEGG: tit:Thit_1351 hypothetical protein. (154 aa)    
Predicted Functional Partners:
ADQ39595.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.971
ADQ40167.1
KEGG: tpd:Teth39_0926 hypothetical protein.
 
 
 0.968
ADQ40168.1
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tit:Thit_1349 DNA methylase N-4/N-6 domain protein.
 
     0.945
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.929
ADQ40303.1
KEGG: ate:Athe_1920 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta.
    
 
 0.842
ADQ40751.1
DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: ate:Athe_1262 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type.
    
 
 0.842
ADQ41113.1
KEGG: tpd:Teth39_0924 DEAD/DEAH box helicase domain-containing protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
   
 0.825
ADQ40170.1
KEGG: tit:Thit_1346 hypothetical protein.
 
     0.802
ADQ40169.1
PFAM: PglZ domain protein; KEGG: tpd:Teth39_0929 alkaline phosphatase domain-containing protein.
 
     0.791
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.757
Your Current Organism:
Caldicellulosiruptor kristjanssonii
NCBI taxonomy Id: 632335
Other names: C. kristjanssonii I77R1B, Caldicellulosiruptor kristjanssonii DSM 12137, Caldicellulosiruptor kristjanssonii I77R1B, Caldicellulosiruptor kristjanssonii str. I77R1B, Caldicellulosiruptor kristjanssonii strain I77R1B
Server load: low (14%) [HD]